Mild Hyperbaric Oxygen Exposure Enhances Peripheral Circulatory Natural Killer Cells in Healthy Young Women
Keywords: Cancer, Natural Killer Cells, Parasympathetic Activity
Title: Mild Hyperbaric Oxygen Exposure Enhances Peripheral Circulatory Natural Killer Cells in Healthy Young Women
Publisher: MDPI Open Access Journal (Print: Life 2023, 13 (2), 408) (Online: 02/01/2023)
Pressure: 1.4 ATA
Oxygen Concentration: 35-40%
Duration: 70 min
Sessions: 1
Conclusion: Exposure to mild HBO could increase the numbers of NK cells possibly mediated by parasympathetic activity enhancement in healthy volunteers. Moreover, the exposure does not cause systemic oxidative stress or an inflammatory response, so it could be used as a beneficial protocol for enhancing immunity. Women’s health complications can be prevented by using mild HBO to maintain autonomic nervous system balance. In addition, the use of mild HBO is gaining popularity across a variety of therapeutic fields, including for sports and relaxation purposes, but there has been a lack of evidence to support its usage for healthy women. The results of the current study should help expand the usage of mild HBO for immune purposes.
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Effects of an early intervention with Hyperbaric Oxygen Treatment on arm lymphedema and quality of life after breast cancer—an explorative clinical trial
Keywords: Breast Cancer, Lymphedema
Title: Effects of an early intervention with Hyperbaric Oxygen Treatment on arm lymphedema and quality of life after breast cancer—an explorative clinical trial
Publisher: Supportive Care in Cancer (Springer), Volume 31, Issue 5, Article number: 313 (2023) MDPI Open Access Journal (Online: 05/01/2023)
Pressure: unknown
Oxygen Concentration: unknown
Duration: unknown
Sessions: 40 (over 8 weeks)
Results: Out of 50 eligible participants, 20 women accepted participation. Nineteen women initiated and completed treatment and follow-up. None of the objective measures of LE severity showed consistent changes during the study period, but participants reported significant improvements in quality of life (QOL) (physical functioning, fatigue, insomnia and breast and arm symptoms), with improvements peaking at 6-month follow-up.
Conclusion: Participants receiving HBOT experienced improved QOL without consistently significant changes in arm mass, volume or lymphatic drainage. These results call for studies into differential effect in patient sub-groups, and a large-scale, randomized placebo-controlled trial with long-term follow-up to assess the effect of HBOT in patients with soft tissue radiation injuries after breast cancer seems warranted.
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